Hemato-Oncology (Pediatric)

The team adopts a multidisciplinary approach so as to offer global care for each patient and ensures that this is adapted to medical, psychological, pedagogical and social aspects.

In addition to caring for patients, the department has a teaching and clinical research mission.   

Our specialities

The Haemato-Oncology Department is specialised in treating children and adolescents with:   

  • cancer (solid tumours and leukaemia)  
  • benign blood diseases  
  • haemophilia and other blood clotting disorders  
  • diseases requiring a haematopoietic stem cell transplant or gene therapy   

The department offers: 

  • a hospitalisation unit that includes a non-sterile sector and sterile sector with isolation rooms and rooms for bone marrow and allogenic and autologous stem cell transplants.   
  • a day hospital that cares for infants, children and adolescents who require further investigation or a treatment that does not require hospitalisation. The day hospital also treats patients with a severe immune deficiency following a bone marrow transplant who require relative isolation.   
  • a functional unit for the care of patients with haemostasis disorders    
  • paediatric haemato-oncology, immunology and rheumatology consultations for the diagnosis and treatment of:   

- Solid tumours
- Malignant haemopathies 
- General haematology 
- Haemophilia and haemostasis disorders 
- Immuno-rheumatology 

The team works in close cooperation with outpatient sectors, home care teams and GPS. 

Our team

équipe oncologie

Equipe Oncologie

recherche hémato huderf

Focus

The functional unit providing care for patients with oncological pathologies is a member of the European Reference Network (ERN PaedCan) that links up European professionals in sharing good practices and treating and supporting children with rare or complex cancers.    

The Haemato-Oncology Department is the reference centre for haemophilia, HemoWaB, together with the Brugmann Hospital and the Liège Hospitals.   

Eurobloodnet Register for rare haematological diseases (drepanocytosis) 

The Haemato-Oncology Department has JACIE accreditation. 

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Teaching

The department's doctors play an active part in teaching interns and postgrads.   

Doctors from the Haemato-Oncology Department participate in the awarding of the Drepanocytosis Interuniversity Diploma organised by the University of Kinshasa.   

Publications

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Oral vinorelbine in young patients with desmoid-type fibromatosis

Authors : Laure Kornreich, Daniel Orbach, Nayla Nicolas, Hervé J Brisse, Pablo Berlanga, Anne-Sophie Defachelles, Ludovic Mansuy, Cécile Verite, Laure Saumet, Marie Karanian, and Nadège Corradini. 

Journal : Tumori Journal. 2023;0(0). doi:10.1177/03008916231169806. 

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Nonmetastatic Rhabdomyosarcoma in Children and Adolescents: Overall Results of the European Pediatric Soft Tissue Sarcoma Study Group RMS2005 Study.

Authors : Gianni Bisogno, MD, PhD; Veronique Minard-Colin, MD, PhD; Ilaria Zanetti, BSc; Andrea Ferrari, MD; Soledad Gallego, MD, PhD; Raquel D´ avila Fajardo, MD, PhD; Henry Mandeville, MD; Anna Kelsey, MD; Rita Alaggio, MD; Daniel Orbach, MD, PhD; Sheila Terwisscha van Scheltinga, MD; Gabriela Guill ´en Burrieza, MD; Myriam Ben-Arush, MD; Heidi Glosli, MD; Peter Mudry, MD; Sima Ferman, MD; Christine Devalck, MD; Anne Sophie Defachelles, MD; Johannes Hendrikus Maria Merks, MD, PhD; and Meriel Jenney, MD, PhD. 

Journal : Journal of Clinical Oncology 41, no. 13 (May 01, 2023) 2342-2349. Published online February 27, 2023. DOI: 10.1200/JCO.22.02093. 

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Adolescents and young adults with rhabdomyosarcoma treated in the European paediatric Soft tissue sarcoma Study Group (EpSSG) protocols: a cohort study.

Authors : Andrea Ferrari, Julia C Chisholm, Meriel Jenney, Veronique Minard-Colin, Daniel Orbach, Michela Casanova, Gabriela Guillen, Heidi Glosli, Rick R van Rijn, Reineke A Schoot, Alison L Cameron, Timothy Rogers, Rita Alaggio, Myriam Ben Arush, Henry C Mandeville, Christine Devalck, Anne-Sophie Defachelles, Beatrice Coppadoro, Gianni Bisogno, Johannes H M Merks. 

Journal : The Lancet Child & Adolescent Health 2022. VOLUME 6, ISSUE 8, P545-554, AUGUST 2022. Published Online June 8, 2022. DOI:https://doi.org/10.1016/S2352-4642(22)00121-3.

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Automated Red Blood Cell Exchange Compared to Manual Exchange Transfusion for Children with Sickle Cell Disease is Cost-Effective and Reduces Iron Overload.

Authors : L Dedeken, PQ Lê, L Rozen, H El Kenz, S Huybrechts, C Devalck, S Diallo, C Heijmans, A Ferster. 

Journal : Transfusion. 2018 Jun;58(6):1356-1362. doi: 10.1111/trf.14575. Epub 2018 Mar 25.